Bioengineering of functional adhesive layers
The aim of WP 2 is to realize a synthetic interlayer between cells and elastomer substrate with optimized topographical properties and deformation mechanisms, leading to long term viability of the biological component.
Research aims at extending current additive manufacturing and electrospinning methods to allow the production of either discrete nanofibrous scaffold membranes, 3D microtruss layers or combinations of the former on an elastomeric substrate. This approach will allow generating new material systems with an optimized mechanical environment for the cells. The interlayers will be designed to offer a biomimetic interface for cells seeding, to host cells also subsurface and to ensure a suitable mechanical transition to the homogeneous elastomer.
People
Jan Rys
Oddný Björgvinsdóttir
Karin Würtz-Kozak
Stephen J. Ferguson Laboratory for Orthopaedic Technology
Lukas Weidenbacher
René Rossi Laboratory for Protection and Physiology, Empa